The Science of Decline
After 40, Your Biology Changes.
The cellular systems that once kept you sharp, energized, and resilient begin to fail. This is not aging — this is biology. And biology can be addressed.
NAD+ Decline by Age 50
NAD+ is the coenzyme that powers every cell in your body. By age 50, levels have dropped by half — crippling energy production and DNA repair. This is the single most impactful cellular change that occurs in midlife.
Mitochondrial Efficiency Lost
Your mitochondria are your cellular power plants. By midlife, they produce 40% less ATP — the energy currency your brain, heart, and muscles run on. Less ATP means less of everything: focus, strength, recovery, drive.
Higher “Inflammaging” Markers
Chronic low-grade inflammation triples between ages 40 and 60, silently accelerating cellular damage throughout the body. It is the invisible force behind nearly every age-related decline.
Start Your Protocol Here
Genesis
NMN · Nicotinamide Mononucleotide
- Supports NAD+ restoration and cellular energy production
- Promotes DNA repair and mitochondrial function
- Backed by peer-reviewed longevity research
You save $7.50 every month
No commitment · Cancel anytime in your account
30-Day Money-Back Guarantee. If you are not completely satisfied, we will refund your order — no questions asked.
The Science Behind YouRenew
Your Cells Know How to Thrive.
They Just Need the Right Signal.
Every product in the YouRenew protocol is built around a single principle: give your body the compounds it already understands, at the concentrations that matter.
NAD+ Declines With Every Decade
NAD+ (Nicotinamide Adenine Dinucleotide) is the molecule your cells use to produce energy, repair DNA, and regulate hundreds of metabolic processes. It is not optional — it is foundational.
By your 40s, your NAD+ levels have already dropped by roughly 50% from their peak. By 60, they can fall to a third of what they were at 20. This decline is not a symptom of aging — research increasingly suggests it is a primary driver of it.
NMN: The Direct Precursor to NAD+
NMN (Nicotinamide Mononucleotide) is the most efficient precursor to NAD+ identified in longevity research. Unlike NAD+ itself, NMN is small enough to be absorbed directly into cells, where it is rapidly converted into NAD+.
Peer-reviewed studies from Harvard, Washington University, and the University of Tokyo have demonstrated NMN's ability to restore NAD+ levels, improve mitochondrial function, and support healthy aging markers in both animal models and human trials.
Explore Genesis NMN →Cellular Energy Production
NAD+ is the essential cofactor in the mitochondrial energy cycle. Restoring NAD+ levels directly supports ATP production — the currency your cells use for every biological function, from muscle contraction to cognitive processing.
Yoshino et al., Cell Metabolism, 2018
DNA Repair & Longevity Pathways
NAD+ activates sirtuins — a family of proteins that regulate DNA repair, inflammation response, and cellular stress resistance. Sirtuin activation is one of the most studied mechanisms in longevity science, linked to extended healthspan in multiple model organisms.
Imai & Guarente, Trends in Cell Biology, 2014
Cognitive Function & Mental Clarity
The brain is one of the most metabolically demanding organs in the body. NAD+ depletion is associated with neuroinflammation and cognitive decline. Restoring NAD+ levels has been shown to support neuroprotection, synaptic plasticity, and mental sharpness in aging populations.
Hou et al., Cell Reports, 2021
Genesis delivers 500mg of pharmaceutical-grade NMN per serving — the clinically studied dose.
Start With Genesis — $49.99Our Promise to You
We Back This Product.
Completely. For 60 Days.
Real cellular change takes time. We know that. So we give you the time to actually feel it — and we stand behind every day of it.
Guarantee
NMN Is Not a Stimulant. It Is a Restoration.
Most supplements promise results in days. We are not most supplements. NMN works by replenishing NAD+ at the cellular level — a process that unfolds over weeks, not hours. Most customers begin noticing meaningful changes in energy, mental clarity, and recovery somewhere between weeks four and eight.
That is why we offer 60 days — not because we have to, but because we want you to have enough time to actually experience what Genesis does. We are confident in the science. We are confident in the quality. And we are confident in you giving it the time it deserves.
If after 60 full days you are not satisfied — for any reason — contact us and we will refund your purchase in full. No return required. No explanation needed. No questions asked.
Start Your 60-Day Trial →What Most Customers Experience
NAD+ levels begin to rise. Most customers notice subtle improvements in sleep quality and morning energy.
Mitochondrial function improves. Sustained energy throughout the day becomes more consistent. Mental clarity sharpens.
The full effect of restored NAD+ becomes clear. Customers report feeling like a younger version of themselves — with the energy, focus, and recovery to match.
GMP Certified Facility
Manufactured in an FDA-registered, GMP-certified facility — the same production standards applied to pharmaceutical drugs, not food products.
Independent 3rd Party Testing
Every batch is independently tested for potency, purity, and the absence of heavy metals and contaminants. We do not ask you to take our word for it.
Made in the USA
Proudly manufactured in the United States. Domestic production means tighter quality control, full traceability, and standards that overseas manufacturing cannot consistently match.
Clean Label. No Compromises.
No fillers, no proprietary blends hiding underdosed ingredients, no unnecessary additives. What is on the label is in the capsule — at the dose the research supports.
"We built YouRenew because we believe the science of longevity should be accessible to everyone. And we back that belief with 60 days and your money."
Begin Your Protocol — Risk Free60-day money-back guarantee · No return required · Cancel subscriptions anytime · Free shipping on orders $75+
Free Resource
The YouRenew
Longevity Protocol Guide
Everything you need to understand the science of cellular aging — and the exact protocol our community uses to fight it.
- ✓ The NAD+ decline timeline — what happens decade by decade
- ✓ How to stack the Core Six Protocol for maximum effect
- ✓ The 8-week onboarding schedule our members follow
- ✓ Key research citations — the studies behind every product
Get Instant Access — Free
Common Questions
Frequently Asked Questions
Everything you need to feel confident about YouRenew — our products, our standards, and our commitment to you.
Every YouRenew product is manufactured in the United States in a certified facility that follows strict quality and safety standards. Our manufacturing partner operates under federally regulated guidelines and undergoes third-party verification to ensure consistency, cleanliness, and product integrity. You can feel confident knowing each product is produced with safety as a top priority.
Yes. Our manufacturing partner follows rigorous quality control processes, including ingredient verification, batch testing, and compliance with Good Manufacturing Practices (GMP). This ensures that what's on the label is exactly what's in the product — nothing more, nothing less.
All YouRenew products are proudly manufactured in the United States in a regulated facility that adheres to strict domestic quality standards.
Our manufacturing partner maintains multiple certifications that reflect a high standard of safety, quality, and compliance:
- NSF/GMP Certification — Confirms adherence to strict Good Manufacturing Practices and FDA-aligned production standards
- FDA Registered Facility — The facility is registered with the FDA and subject to inspection and compliance requirements
- UDAF Certification — Verifies compliance with state-level food safety and manufacturing regulations
- Natural Products Association (NPA) — Demonstrates commitment to responsible sourcing and ingredient integrity
- Manufactured in the USA — Ensures products meet stringent U.S. production standards
These certifications are not easy to obtain — they require ongoing audits, inspections, and operational discipline.
NSF certification verifies that the manufacturing facility complies with strict Good Manufacturing Practices (GMP), which are aligned with FDA regulations. This includes controls around ingredient sourcing, production processes, sanitation, record-keeping, and quality assurance.
In simple terms: it ensures your supplements are made consistently, safely, and to a verified standard.
This is an important distinction. Dietary supplements are not "FDA-approved" in the same way as pharmaceutical drugs. However, our manufacturing facility is FDA registered and compliant, meaning it must follow federal regulations and is subject to inspection.
This ensures accountability, traceability, and adherence to safety standards.
We prioritize high-quality, responsibly sourced ingredients. Our manufacturing partner works with vetted suppliers and follows strict sourcing protocols to ensure purity, potency, and consistency.
Our formulations are designed to be clean and effective. While some inactive ingredients may be necessary for stability or delivery (such as capsules), we avoid unnecessary fillers and focus on functional, purposeful ingredients.
Many of our products feature natural ingredients and are aligned with standards recognized by organizations like the Natural Products Association (NPA), which supports responsible sourcing and transparency.
Results vary depending on the product and individual. Some customers notice benefits within days, while others may take a few weeks of consistent use. Supplements are most effective when taken regularly as part of a healthy lifestyle.
In many cases, yes — our products are designed to complement one another. However, we always recommend reviewing labels and consulting with a healthcare professional if you have specific conditions or concerns.
Our products are designed for general wellness, but individuals who are pregnant, nursing, taking medication, or managing a medical condition should consult a healthcare professional before use.
We've built YouRenew around one simple principle: do it right, or don't do it at all. That means:
- Partnering with a certified, U.S.-based manufacturer
- Producing in FDA-registered, inspected facilities
- Following NSF/GMP standards for quality and consistency
- Prioritizing clean, effective formulations
We don't cut corners — and we don't expect you to just take our word for it.
Yes. We believe in full transparency. Documentation for our manufacturing certifications is available and can be provided upon request, including NSF/GMP certification and FDA facility registration.
Real People. Real Results.
What the YouRenew Community Is Saying